Abstracts

A Case-Control Study Comparing New Onset Epilepsy in Patients Younger and Older Than 65 Years

Abstract number : 3.156
Submission category : Clinical Epilepsy-Adult
Year : 2006
Submission ID : 6457
Source : www.aesnet.org
Presentation date : 12/1/2006 12:00:00 AM
Published date : Nov 30, 2006, 06:00 AM

Authors :
Vitaliy Koss, Peyman Andalib, Sigmund Jenssen, and Jyoti Pillai

The elderly in United States are representing a greater percentage of the general population than before. This age group has increased risk of developing epilepsy as compared to those who are younger. Previous reports indicate that in this age group the clinical presentation of new onset epilepsy is frequently varied and obvious epileptic seizures are sometimes not reported. Epileptiform activity in the EEG (EA) is highly specific for epilepsy when acute symptomatic conditions and PLEDS are excluded., We reviewed chief complaint (CC) and EEG findings in patients minimum 65 years old with EA referred to the neurophysiology laboratory at Hahnemann University Hospital between October 2004 and April 2006 for possible new onset seizures.
We compared them to control group (patients younger then 65 years).
Patients with known additional acute CNS event, PLEDS, recent medication change, severe metabolic derangement or prior history of epilepsy were excluded., See Table for results.
Fall, electrographic diffuse slowing, organic brain syndrome and medical comorbidities was more frequent (p[lt]0.05) in the elderly group, while there was a trend (p[lt]0,10) of confusion and temporal lobe spikes to be more frequent in this group as compared to controls., Fall, confusion, diffuse slowing in the EEG and temporal lobe spikes are more common with onset of epilepsy in the elderly compared to younger adults. Organic brain syndrome and medical comorbidities are also more common.[table1],
Clinical Epilepsy