Guidelines

The American Epilepsy Society is a trusted source of evidence-based clinical guidance for epilepsy specialists and other healthcare providers. 

Open for Comment

The American Epilepsy Society (AES) and the International League Against Epilepsy-North America (ILAE-NA) Epilepsy Disparities Joint Task Force has prepared draft recommendations to address epilepsy health care disparities.

The task force invites public comment on the draft recommendations. All input will be considered but may or may not be incorporated in the final recommendations. The AES/ILAE-NA Taskforce will convene to discuss all comments and any potential modifications to the draft.

Questions? Please contact Dr. Shawna Strickland at sstrickland@aesnet.org.

AES Clinical Guidance in Development

• AES Management of Infantile Epilepsies Systematic Review Update and Guideline
• AES/ACNS Intraoperative Electrocorticography (ECoG) Systematic Review and Guideline
• AES/CNS Epilepsy Surgery Systematic Review and Guideline
• AES/NCS Status Epilepticus Systematic Review and Guideline

Evidence-Based Guidelines

• Teratogenesis, Perinatal, and Neurodevelopmental Outcomes After In Utero Exposure to Antiseizure Medication: Practice Guideline from AAN, AES, and SMFM (May 2024)
• Practice Guideline Update Summary: Efficacy and Tolerability of the New Antiepileptic Drugs I: Treatment of New-onset Epilepsy
• Practice Guideline Update Summary: Efficacy and Tolerability of the New Antiepileptic Drugs II: Treatment-resistant Epilepsy
• Practice Guideline Summary: SUDEP Incidence Rates and Risk Factors: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Epilepsy Society
• Practice guideline summary: Use of fMRI in the presurgical evaluation of patients with epilepsy

• Evidence-Based Guideline: Treatment of Convulsive Status Epilepticus in Children and Adults: Report of the Guideline Committee of the American Epilepsy Society
  • Guideline for Treatment of Prolonged Seizures in Children and Adults 
  • A Treatment Algorithm that Comprises Three Phases of Treatment 
• Evidence-based Guideline: Management of First Unprovoked Seizure in Adults
• Evidence-based Guideline: Evaluation and Management of Concussion in Sports
• Evidence-based Guideline: Vagus Nerve Stimulation for the Treatment of Epilepsy
• Evidence-based Guideline: Antiepileptic Drug Selection for People with HIV/AIDS

2020 AES CPG Development Manual

AES Clinical Practice Guideline Development Manual (2020)
This manual outlines principles and processes intended to guide AES-led workgroups in the development of high-quality clinical guidance products consistent with broadly accepted, evidence-based principles and processes appropriate to the needs of the epilepsy clinical community.