AN EVALUATION OF THE RELATIONSHIP BETWEEN QUALITY OF LIFE AND MOOD IN AN OUTPATIENT EXERCISE STUDY
Abstract number :
1.261
Submission category :
Year :
2002
Submission ID :
1352
Source :
www.aesnet.org
Presentation date :
12/7/2002 12:00:00 AM
Published date :
Dec 1, 2002, 06:00 AM
Authors :
James W. McAuley, Lucretia Long, James L. Moore, Kimford J. Meador, Janet Buckworth. Comprehensive Epilepsy Program, The Ohio State University Medical Center, Columbus, OH; Departments of Neurology & Pharmacology/Toxicology, Medical College of Georgia, Au
RATIONALE: Based on previous literature describing the relationship between quality of life and mood assessments in patients with epilepsy, we examined the behavioral data from our recently-completed study evaluating the effects of a structured outpatient exercise program on outcomes in patients with epilepsy. We hypothesize that there is a relationship between patients[ssquote] quality of life and mood. At the end of this activity the participants should be able to discuss the relationships between these two behavioral measures and its influence by exercise.
METHODS: This prospective, randomized, parallel, controlled study spanned 12 weeks. Twenty-eight patients were randomly assigned to a supervised exercise program (EXERCISE) or instructed to continue with their current level of activity, with no planned interventions (CONTROL). The EXERCISE group exercised for one hour on three separate occasions per week for the 12-week study. All patients underwent baseline clinical, physiological, and behavioral evaluation. As part of the behavioral measures, patients completed the 65-item Profile of Mood States (POMS) and Quality of Life in Epilepsy Inventory-89 (QOLIE-89) at baseline and week 12.
RESULTS: Twenty-three patients completed the 12-week study. There were no differences in baseline scores for either measure between the two patient groups. The overall QOLIE-89 score improved from baseline to week 12 in the EXERCISE group (p=0.031), while the CONTROL group score did not change (p=0.943). In the EXERCISE group, two of the domain scores were significantly improved at week 12 (physical function and health perceptions). Separate repeated measures MANOVAs were conducted on the POMS data for each group to determine changes from baseline to the end of the 12-week exercise program. There were no differences over time for the CONTROL group, but there was a significant multivariate effect for time for the EXERCISE group (p = 0.05). Repeated measures ANOVAs for each POMS scale and for total mood were conducted for the EXERCISE group. Vigor improved and total mood scores decreased from the beginning to the end of the program. The detailed relationships between the domains of each measure will be presented and discussed.
CONCLUSIONS: The results suggest that exercise may modulate both mood and quality of life in patients with epilepsy.