Anterior temporal lobectomy versus selective amygdalohippocampectomy in patients with mesial temporal lobe epilepsy.
Abstract number :
2.240
Submission category :
9. Surgery / 9A. Adult
Year :
2016
Submission ID :
194561
Source :
www.aesnet.org
Presentation date :
12/4/2016 12:00:00 AM
Published date :
Nov 21, 2016, 18:00 PM
Authors :
Fabio A Nascimento, Toronto Western Hospital, University of Toronto, Canada; Luana Gatto, Universidade Federal do Paraná; Carlos Silvado, Universidade Federal do Paraná; Maria Mader, Universidade Federal do Paraná; Marlus Moro, Universidade Federal do Par
Rationale: To contribute our experience with surgical treatment of patients with mesial temporal lobe epilepsy (mTLE) undergoing anterior temporal lobectomy (ATL) or selective amygdalohippocampectomy (SelAH). Methods: This is a retrospective observational study. The sample included patients with medically refractory mTLE due to unilateral mesial temporal sclerosis who underwent either ATL or SelAH, at Hospital de Clinicas ?" UFPR, from 2005 to 2012. We report seizure outcomes, using Engel classification, cognitive outcomes, using measurements of verbal and visuospatial memories, as well as operative complications. Results: Sixty-seven patients (33 ATL, 34 SelAH) were studied; median follow-up was 64 months. There was no statistically significant difference in seizure or neuropsychological outcomes, although verbal memory was more negatively affected in ATL operations on patients' dominant hemispheres. Higher number of major complications was observed in the ATL group (p = 0.004). Conclusions: Seizure and neuropsychological outcomes did not differ. ATL appeared to be associated with higher risk of complications. Funding: This study was not funded.
Surgery