Abstracts

To study the association among temporal lobe epilepsy (TLE) with mesial temporal sclerosis (MTS) and psychosis. Evaluation of clinical data in a group of patients with TLE with MTS and associated psychosis. Out of 46 patients with epilepsy associated with psychosis, we have selected 23 with MTS diagnosis. Average age of onset of epilepsy was 7,8 years old (DP=5,83), 28 years old (DP=11,2) for psychosis, with an average difference of onset for both diagnoses of 20,1 years (DP=11,38), 82,6% had interictal psychosis and 30,4% posictal. There were no case of ictal, pre-ictal or alternating psychosis. Most patients presented schizophreniform presentations. TLE with MTS is a frequent epileptic syndrome, specially important for its clinical refractoriness, while psychosis is one of the most important psychiatric conditions associated with epilepsy. The elevated number of posictal cases evolving to interictal psychosis in these patients points to the need of incisive treatment of this epileptic syndrome.