Bilateral ischemic optic neuropathy after subdural electrode placement for epilepsy surgery and treatment with erythropoietin
Abstract number :
2.011;
Submission category :
9. Surgery
Year :
2007
Submission ID :
7460
Source :
www.aesnet.org
Presentation date :
11/30/2007 12:00:00 AM
Published date :
Nov 29, 2007, 06:00 AM
Authors :
P. Widdess-Walsh1, 3, R. E. Turbin2, A. C. Tutela II2, E. B. Geller1, H. L. Bennett2, W. K. Doyle1, 4, O. Devinsky1, 3
Rationale: A 21 year old woman with inactive Hashimoto’s encephalopathy underwent subdural EEG electrode placement for intractable partial epilepsy. EEG and MEG had localized her epilepsy to the left temporo-occipital regionMethods: Case reportResults: Forty-five minutes after the end of surgery, she complained of blindness; reporting no visual perception in either hemifield. Her subdural grids were removed. She had developed bilateral posterior ischemic optic neuropathy, a perioperative complication not previously reported with this surgery. Her vision improved after treatment with Erythropoietin (Epo), a putative neuroprotective agent not previously used for this indication. Conclusions: This is the first case of ischemic optic neuropathy associated with subdural electrode placement for epilepsy surgery that we are aware of. There was significant improvement in her vision following the administration of Epo, a putative neuroprotective agent, atypical in the natural course of perioperative ischemic optic neuropathy. The use of Epo for perioperative ischemic optic neuropathy warrants further study in clinical trials
Surgery