Authors :
Presenting Author: Anita Datta, MD, FRCPC – University of British Columbia
Shishir Duble, MD – University of British Columbia
Rationale:
Positive spike wave discharges (PSW) on EEG are well-documented in neonates, but data regarding their significance in other populations are limited. This study aimed to assess the clinical significance of PSW in children aged 1 month to 19 years at a single tertiary care center over approximately three decades.
Methods:
Clinical information of children with focal PSW (n=326) was compared to control patients with focal negative IEDs (n=898).
Results:
From 77,500 pediatric EEGs in our laboratory from 1992 to 2020, PSW were identified in 445 (0.57%) children, of which 326 met inclusion criteria. PSWs were located in the following brain regions: occipital (139), central (65), frontal (63), temporal (43), parietal (9) and centro-temporal (7). PSW patients had a younger median age of seizure onset than control patients [1.1 years (0.30, 4.00) vs 4 years (1.3, 7.5), p < 0.001].