COGNITIVE DEFICITS IN PATIENTS WITH BENIGN ROLANDIC EPILEPSY
Abstract number :
2.189
Submission category :
Year :
2005
Submission ID :
5493
Source :
www.aesnet.org
Presentation date :
12/3/2005 12:00:00 AM
Published date :
Dec 2, 2005, 06:00 AM
Authors :
1-4Marcelo E. Lancman, 2Bruce Roseman, 1-4Olgica Laban, 3Malkin Elfrida, 1Sarala Devi, 4Steven Thompson, 1Lorna Myers, and 1Michael Cohen
To determine the frequency and characteristics of cognitive deficits in patients with Benign Rolandic Epilepsy (BRE). We studied 41 consecutive patients admitted for video-EEG monitoring who were diagnosed with BRE. A clinic generated questionnaire regarding cognitive, behavioral, and academic status was administered to the patient[apos]s caregivers. Seventeen patients were females and 24 males. Median age at the time video-EEG was performed was 8.5 years; median age at onset of seizures was 5 years. Interictal EEG was bilateral in 24 cases, localized to the left hemisphere in 10 and to the right in 7. The spike source was somehow atypical in 10 cases. Twenty-four patients were on AEDs at the time of video-EEG monitoring. Of the 41 questionnaires, 32 we completed. Cognitive deficits were found in 21 patients. These mainly included speech-language, learning and attention deficits, with most of these children receiving special education interventions. Benign Rolandic Epilepsy appears to be associated with broadly construed neurodevelopmental impairments as observed in a population of tertiary patients. Preliminary results suggest that there is a subpopulation of children with BRE who present with a higher level of neurocognitive deficits than previously suspected.