Abstracts

Rationale: The comparism of the outcomes for patient who had undergone Stereotactic laser ablation for medically refractory epilepsy to the patients who have undergone traditional anterior temporal lobectomies for medically refractory epilepsy in University of Texas Health science center in San Antonio. The study will compare seizure outcomes and also neuropsychological outcomes, with a baseline exam before the procedure and post operative exam 1 year after the procedure. It will be beneficial to have head to head study especially with neuropsychological outcomes to access the cognitive deficit and make an informed decision with the patient. _x000D_
Methods: This is a retrospective, single center, comparism research, studying patients who had epilepsy surgeries- Anterior temporal lobectomy and LITT. Engel classification is used to access the post op seizure freedom. Baseline characteristics are charted, as are age of onset, age of surgery, etiology, types of seizures, MRI, VEEG/SEEG, Neuropsych evaluation pre and post op, post op complications, seizure control at 1 year post procedure, medications at 1 year.

Results: The patients were grouped according to the side of surgery left and right and also type of procedure they received - ATL or LITT. The patients were further grouped and divided on basis of sex, mean age of onset, mean age at surgery, mean duration of epilepsy, seizure types, lesion or non lesional MRI, lateralized VEEG, ipsilateral PET, ipsilateral SPECT, post op neurological complications, and seizure outcomes at 1 year post op. Neuropshycological outcomes were grouped for verbal memo, visual memory, logical memory, list learning, recognition, anxiety, depression, overall quality of life.

Conclusions: There was better seizure outcome seen with the anterior temporal lobectomy but the neuropsychological outcomes were better with LITT procedure.

Funding: None