Cortical Dysplasia and Mesial Temporal Sclerosis in Temporal Lobe Epilepsy -Preoperative Clinical Feature and Surgical Outcome Between Patients with Dural Pathology and Patients with Mesial Temporal Sclerosis
Abstract number :
2.214
Submission category :
Year :
2000
Submission ID :
1265
Source :
www.aesnet.org
Presentation date :
12/2/2000 12:00:00 AM
Published date :
Dec 1, 2000, 06:00 AM
Authors :
Joong-Koo Kang, Suk-Yun Kang, Sang-Ahm Lee, Jung-Kyo Lee, Sung-Hye Park, Shin-Kwang Khang, Kyu-Hwan Kwak, Ulsan Univ, Coll of Medicine, Asan Medical Center, Seoul, South Korea; Dept of Neurology, Ulsan Univ, Seoul, South Korea; Dept of Neurosurgery, U
RATIONALE: Mesial temporal sclerosis(MTS) is well-known cause of temporal lobe epilepsy. Coexistence with cortical dysplasia(CD) has been reported, but its role is not well recognized. This study aims to determine whether there is any difference about clinical feature and surgical outcome between patients with MTS and coexistent CD(group 1) and patients with isolated MTS( group 2). METHODS: Retrospectively, surgical series of 45 patients (male:22, female: 23) diagnosed as temporal lobe epilepsy were reviewed. We excluded patients who had another pathology(e.g., tumor, vascular malformation) except MTS or CD. The pathology, case histories,EEG and surgical outcome were compared. RESULTS: There was a tendency for group 1 patients to have earlier seizure onset age(10.9?6.35 versus 14.5?6.03, p=0.06). There was no statistically significant difference in the history of febrile convulsion(68.4% versus 53.8%, p>0.16). No statistically significant difference between groups were also found in disease duration, the head trauma, seizure frequency, EEG and surgical outcome. CONCLUSIONS: CD in MTS appears to have an influence on seizure onset. Additional studies in larger groups of patients are needed.