Diagnostic Added Value of High-Density Versus Low-Density EEG Recordings
Abstract number :
2.035
Submission category :
3. Neurophysiology / 3C. Other Clinical EEG
Year :
2018
Submission ID :
501335
Source :
www.aesnet.org
Presentation date :
12/2/2018 4:04:48 PM
Published date :
Nov 5, 2018, 18:00 PM
Authors :
Anders B. Justesen, Danish Epilepsy Centre and University of Southern Denmark; Christian Skaarup, Danish Epilepsy Centre and University of Southern Denmark; and Sándor Beniczky, Danish Epilepsy Centre, Aarhus University.
Rationale: High-density EEG recordings (HD-EEG) provide more accurate data for localizing epileptiform discharges (EDs) compared to low-density EEG recordings (LD-EEG). There are anecdotal reports suggesting that HD-EEG records EDs which are missed by LD-EEG. Our aim was to investigate the added value of HD-EEG. Methods: We have prospectively recorded HD-EEG in 30 consecutive patients. HD-EEG (30-90 minutes) was recorded with 256 electrodes. Spike-clusters were identified in HD-EEG and separately in LD-EEG recordings (25 electrodes) from the down-sampled HD-EEG recordings and from preceding long-term video-EEG monitoring (LTM) using 25 electrodes, in the same patients. Results: Forty-three spike-clusters were identified in the LTM recordings, 39 in the LD-EEG and 41 in the HD-EEG recordings. Conclusions: The higher spatial sampling of HD-EEG increased modestly the yield of identified spike clusters compared to LD-EEG recordings (two additional spike-clusters = 5%). However, due to the shorter recording-time of HD-EEG, compared to LTM, two spike-clusters (5%) were missed. Diagnostic yield depends both on the electrode array and on the duration of the recording. Funding: None