Abstracts

Rationale: To reveal the difference of intelligence functioning between idiopathic generalized and partial epilepsy in newly diagnosed childhood patients. Methods: Fifty-five patients with newly diagnosed idiopathic childhood epilepsy performed Wechsler Intelligence Scale for Children (WISC) before antiepileptic drugs (AEDs) at Sanggye Paik Hospital. The patients were divided into three groups: generalized, partial and unclassified epilepsy. Results: The WISC was performed at 100.27±27.8 months. According to seizure types, results were as follows; 1) generalized seizure (n=14) idiopathic generalized epilepsy (n=11), childhood absence epilepsy (n=1) and juvenile absence epilepsy (n=2)was 25.5%(14/55): 2) partial epilepsy (n=37) was 62.7% (37/55) benign childhood epilepsy with centrotemporal spikes, BCECTS (n=16), benign epilepsy with occipital paroxysm (n=5) and unclassified partial epilepsy (n=16):3)unclassified epilepsy (n=4) was 7.3% (4/55). Mean Full scale IQ(FSIQ) of all 55 patients (Male 21, Female 34) was 106.3±12.0. When compared with generalized epilepsy and BCECTS, the difference in FSIQ and verbal IQ (VIQ) was not significant, but that in performance IQ was significant low in BCECTS (110.3±6.6 vs 105.3±14.0 months, P=0.006). There was no correlation between the level of IQ and the duration of epilepsy, the onset age of epilepsy, and seizure frequency before the examination. Conclusions: BCECTS has lower VIQ than idiopathic generalized epilepsy. And the follow-up intelligence functioning test after AEDs is required.