Dipole Theory Approach to Irreplaceable Diagnostic Values of Nasopharyngeal Electrodes in Temporal Lobe Epilepsy
Abstract number :
1.163
Submission category :
3. Neurophysiology / 3G. Computational Analysis & Modeling of EEG
Year :
2023
Submission ID :
21
Source :
www.aesnet.org
Presentation date :
12/2/2023 12:00:00 AM
Published date :
Authors :
Presenting Author: Soo Hwan Yim, MD – Ulsan University College of Medicine
Kyoung Heo, Medical professor – Professor, Department of Neurology, Yonsei University College of Medicine
Rationale: Since the 10-20 electrode system has limitations in diagnosing the basal and mesial temporal aspect, NP and anterior temporal electrodes have been introduced among additional electrodes. In the meantime, NP and anterior temporal electrodes have been studied and only focused on the superiority of detecting spikes in temporal lobe epilepsy. However, considering the attachment position of each electrode based on the dipole theory, it can be assumed that the two electrodes cover different areas in temporal lobe epilepsy.
Methods: EEGs diagnosed with temporal lobe epilepsy (N=229) were analyzed simultaneously by attaching NP and anterior temporal electrodes. In case of discrepancy of EEG interpretation, final EEG Interpretations among three epilepsy experts made a consensus on three EEG interpretations. Detected spike notification was performed through the Curry 9® program for secondary analysis of source localization. Source location was performed using individual brain MRI data.
Results: The entire epileptiform discharges (2,721 spikes /n=175) were identified in the study: the group (734 spikes/n=48) in which epileptiform discharges were detected only with NP electrodes and the group (1,987 spikes/n=127) in which epileptiform discharges were simultaneously detected in both NP electrodes and scalp EEG. Only detected epileptiform discharges in NP electrodes showed clustering dipole in basal and mesial temporal aspects. However, simultaneously detected epileptiform discharges in both NPE and scalp EEG located at frontotemporal and lateral temporal aspects except the mesial and basal temporal lobe.
Conclusions: In the case of applying both NP and anterior temporal electrode, the diagnostic sensitivity of EEG among temporal lobe epilepsy was increased. The NP electrode can identify the epileptiform discharge in the mesial and basal temporal area that the anterior temporal electrode cannot be detected. In other words, NP electrodes have irreplaceable diagnostic value in areas not confirmed by the existing 10-20 electrode system with the anterior temporal electrode.
Funding: This research was supported by the Ulsan University Research Fund.
Neurophysiology