Abstracts

Rationale: HIV is a lymphotropic and neurotropic virus and there are three types of onset of the disease in the central nervous system (CNS): 1) mild symptoms; 2) progressive encephalophathy; 3) static encephalopathy. The pathologic founds are: cortical and subcortical atrophy, encephalitis; neuronal apoptosis; difuse leucoencephalopathy and calcifications of the basal ganglia. EEG abnormalities are associated to cortical lesions and includes slow alpha in the background activity, excess of rapid activity, clusters of intermittent slow or sharp waves.To analyse EEGs from children whose mothers were HIV positive and accompanied in a terciary level university hospital (Hospital de Clínicas / UFPR) between 2001 and 2008 and compare the EEGs from infected and soroverters children. Methods: There were 32 children divided into 2 groups: group 1) infected children and group 2) soroverted children. The exams were performed in analogic equipment Nihon-Koden with 21 channels, scalp electrodes disposed according to the International System 10-20, time registering of at least 30 minutes in awake and sleep, photic stimulation between 2 and 30 Hz and voluntary hyperventilation, if possible. There were analysed background activity (normal or abnormal) and the presence or not of epileptiform activity. Statistic analyses was realized with qui-square. Results: Group 1 included 15 children and group 2 included 17 children. Among children in group 1, 10 had normal EEG (67%), 4 had mild desorganization in the background activity (27%) and 1 child had epileptiform activity (6%). Among children in group 2, 13 had normal EEG (76%), 3 had mild desorganization in the background activity (17%) and 1 child had epileptiform activity (6%). Nobody among the two groups had seizures and nobody received antiepileptic drugs. Conclusions: HIV infection can cause inespecific alterations in the background activity in those children. In our grup had no differences beteween brazilian chindren infected with HIV and seroreverter children..