EEG PATTERNS IN MILD COGNITIVE IMPAIRMENT
Abstract number :
1.352
Submission category :
Year :
2003
Submission ID :
3820
Source :
www.aesnet.org
Presentation date :
12/6/2003 12:00:00 AM
Published date :
Dec 1, 2003, 06:00 AM
Authors :
Rabia B. Choudry, Sigmund Jenssen, Carol F. Lippa Neurology, Drexel University College of Medicine, Philadelphia, PA
Mild Cognitive Impairment is defined as patients with memory deficits who do not fulfill the criteria, but may develop Alzheimer[rsquo]s Disease. While Mini Mental Status Examination, neuropsychology and neuroimaging are widely used, the role of EEG has not been established in the diagnosis of MCI or its progression to dementia. Our objective is to define EEG patterns consistent with MCI.
We reviewed 83 charts of patients with MCI. We compared the MMSE scores to the presence or absence of slowing on EEG using simple logistic regression.
Eighteen of the 83 patients (21.7%) had EEGs. Mean age was 59 (34-78). Median MMSE score was 28 (25-30).
Six EEGs (33%) showed focal slowing, one with sharp waves. Three (16.7%) had only diffuse slowing. Two (11%) had increased beta. Nine (50%) were normal. No correlation was found between MMSE scores and the presence or absence of slowing on EEG.
50% of EEGs showed diffuse or focal slowing. There is a risk of overrepresentation of abnormal studies since only 21.7% of patients had EEGs. Larger studies are needed to better define the EEG characteristics of patients with MCI to assist in the early diagnosis of dementia.