Abstracts

Summary: fMRI has been used successfully in epilepsy patients to map language networks and predict outcome. Only recently has the fMRI of memory begun to elucidate memory networks and inform practice. This IW is designed to provide the current state of fMRI memory investigations and applications in patients with localization related epilepsy. Dr. Mary Pat McAndrews will discuss work on activation in the mesial temporal regions and other components of the autobiographical memory network. She will focus on the relationship of activation strength to pre- and post-operative memory performance as well as electrophysiological data from patients with depth electrode recordings. Dr Silvia Bonelli will present data on material-specific based paradigms targeted to activate mesial temporal regions and their relationship to post operative memory outcomes. This work will also examine the issue of functional capacity vs. functional reserve in relation to hippocampal activation and surgical outcomes. Dr Madison Berl will present investigations on working memory with emphasis on the complicated relationships between working memory and language. The workshop will focus on obstacles to fMRI memory investigations, challenges of paradigm design and execution, and confounding factors of cross domain interference, and outcomes determination.