Abstracts

Rationale: Infraslow activity (ISA) has been found to be helpful to localize ictal onset region in adult epileptic patients. There are no reports of infraslow activity in children with epilepsy undergoing presurgicalscalp and intracranial monitoring. The purpose of the study w as completed to assess theictal baseline shifts and infraslow activity in five consecutive children w ho underwent epilepsysurgery.Methods: A retrospective EEG analysis w as completed of five children w ho underw ent conventional prolonged video LTM-EEG and subsequently underwent successful resective epilepsy surgery. ISAand ictal shifts w ere identified using previously recommended settings with 0.016 Hz, 0.1 Hz, 0.2 and open pass filters respectively. A total of twenty seizures w ere analyzed.Results: The recorded analyzed seizures had over 90% correlate demonstrated by a clear ictal baseline shift and clear identifiable localized infraslow activity that was demostrated with the recommended filters settings, and not identifible with conventional frequency band (CFB) analysis.Conclusions: Identification of infraslow activity and ictal onset baseline shifts can be easily achieved in children undergoing evaluations for Epilepsy surgery. Current modern amplifiers allow accurate analysis during scalp and intracranial EEG recordings, specifically applying using protocols that use infraslow activity.