Neonatal Status Epilepticus: An Under-Recognized Phenomenon
Abstract number :
1.203
Submission category :
4. Clinical Epilepsy / 4B. Clinical Diagnosis
Year :
2018
Submission ID :
496347
Source :
www.aesnet.org
Presentation date :
12/1/2018 6:00:00 PM
Published date :
Nov 5, 2018, 18:00 PM
Authors :
Coffino Samantha, University of California - San Francisco; Sehrash Shabbir, Columbia University; Marie-Coralie Cornet, University of California - San Francisco; Tristan Sands, Columbia University; Eric Armour, Columbia University; Tiffani L. McDonough, C
Rationale: Neonatal status epilepticus (NSE) is a relatively new concept, first defined in 2007 as “continuous seizure activity > 30 minutes or recurrent seizures lasting > 30 minutes without definite return to baseline” (Pisani et al, Neonatal status epilepticus v. recurrent neonatal seizures. Neurology. 2007; 69: 2177-85). The current definition requires at minimum 30 minutes before identification of NSE, potentially delaying appropriately aggressive treatment. The goal of this study is to describe the time to recognition, the clinical and EEG characteristics, treatment patterns and response, as well as outcomes in neonates diagnosed with NSE by the current established definition, as well as by more strict definitions. Methods: This is a retrospective observational study of neonates born between 2008-2016 at University of California, San Francisco. Neonates that met three progressively more strict definitions for NSE were selected and grouped according to seizure duration (seizure duration >30 min, > 15 min, and > 5 min). Their charts were reviewed and data analysis was performed in order to compare the groups<./p>
