Abstracts

Omitting Hyperventilation in Electroencephalogram during the COVID-19 Pandemic May Reduce the Diagnostic Rate of Juvenile Myoclonic Epilepsy

Abstract number : 2.413
Submission category : 3. Neurophysiology / 3C. Other Clinical EEG
Year : 2022
Submission ID : 2232869
Source : www.aesnet.org
Presentation date : 12/4/2022 12:00:00 PM
Published date : Nov 22, 2022, 05:28 AM

Authors :
Keisuke Hatano, MD – Seirei Hamamatsu General Hospital; Ayataka Fujimoto, MD, PhD – Seirei Hamamatsu General Hospital; Keishiro Sato, MD – Seirei Hamamatsu General Hospital; Takamichi Yamamoto, MD, PhD – Seirei Hamamatsu General Hospital; Hideo Enoki, MD, PhD – Seirei Hamamatsu General Hospital

This is a Late Breaking abstract

Rationale: To prevent the spread of coronavirus disease 2019 (COVID-19), hyperventilation (HV) activation has been avoided in electroencephalograms (EEGs) since April 2020. The influence of omitting HV in EEG on epilepsy diagnosis remains uncertain. We hypothesized that EEGs with HV would show more interictal epileptiform discharges (IEDs) than EEGs without HV in patients with juvenile myoclonic epilepsy (JME)._x000D_
Methods: We reviewed the EEGs of patients with JME who underwent EEG both with and without HV from January 2019 to October 2021 in our institution and compared IEDs between EEG with and without HV._x000D_
Results: This study analyzed 23 JME patients. The IED-positive rate was significantly higher in EEG with HV (65.2%) than in EEG without HV (34.8%, p=0.016). Mean ± standard deviation number of IEDs per minute was significantly larger during HV (1.61±2.25 ×10-1) than during non-activation of both first EEG (0.57±0.93 ×10-1, p=0.039) and second EEG (0.39±0.76 ×10-1, p=0.009)._x000D_
Conclusions: In JME patients, performing HV during EEG may increase IEDs and appears to facilitate an accurate diagnosis of epilepsy.

Funding: This research received no external funding.
Neurophysiology