Overweight and Obesity in Patients with Epilepsy
Abstract number :
3.249
Submission category :
6. Cormorbidity (Somatic and Psychiatric)
Year :
2023
Submission ID :
707
Source :
www.aesnet.org
Presentation date :
12/4/2023 12:00:00 AM
Published date :
Authors :
Presenting Author: Magdalena Bosak, MD PhD – Jagiellonian University
Kamil Wężyk, MD – Jagiellonian University
Rationale: Overweight and obesity are a major civilization problem, which is relatively little studied in patients with epilepsy (PWE). The aim of the study was to determine the risk factors of these conditions and to compare PWE with general population
Methods: The study included 401 consecutive PWE treated in the outpatient clinic over the years 2020 through 2021. Their weight and height were measured, BMI was calculated, and information on demographic data, type and treatment of epilepsy, remission, degree of disability was collected. An age and sex-matched control group was selected for comparison
Results: A total of 401 patients (247; 61.6% women), median age 33.0 years, were included. The majority were patients with focal epilepsy (292 patients, 72.8%). BMI > 25 was found in a half of the cohort (197, 49.1%). The overweight and obese patients were older (38.0 vs 29.0 years, p< 0.001), had later epilepsy onset (17.0 vs 15.0, p = 0.016) and longer epilepsy duration (17.0 vs 14.0, p = 0.011). In this group, there were more patients with focal epilepsy (156, 79.2% vs 136, 66.7%, p = 0.005) and a disability certificate (100, 50.8% vs 76, 37.3%, p = 0.007. There were fewer people with higher education (41, 21.9% vs 76, 38.8%, p< 0.001) and currently employed (73, 37.2% vs 109, 53.7%, p = 0.001). There were no significant differences in the currently used anti-seizure medications. In a multivariate logistic regression model, age (OR 1.06 [1.03-1.09], p< 0.001) and male sex (OR 1,85 [1,15-2,97], p = 0.011) were identified as independent risk factors for overweight/obesity in PWE. In the control group, BMI >
Cormorbidity (Somatic and Psychiatric)