Abstracts

RATIONALE: To correlate Engel[ssquote]s classification of postoperative outcome and the proposal for a new classification of outcome with respect to epileptic seizures of ILAE in a study of prognostic factors in temporal lobe epilepsy surgery.
METHODS: We analyzed 41 consecutive patients who underwent temporal lobe epilepsy surgery between 1997 and 2000 in our Epilepsy Unit. We analyzed the following parameters: age of onset, time passed since first non-febrile seizure, presence of simple partial seizures, risk factors for developing epilepsy, presurgery seizure frequency, type of lesion in brain MRI, distribution of interictal epileptiform activity, type of ictal EEG onset, use of intracranial EEG recordings, results of neuropsychological assessment and Wada test, surgical procedure and type of lesion in pathological study. For evaluating outcome we used the class assigned in the last visit using both Engel[prime]s and ILAE[prime]s classification of outcome. T-test and Anova test were used for statistical analysis.
RESULTS: Similar results were obtained with both classifications. The presence of unilateral interictal epileptiform activitity and of temporal unilateral ictal EEG onset as well as the lack of use of intracranial recordings were associated (p[lt]0,05) with a better prognosis using both classifications.Having more than twenty seizures per month presurgery and the presence of non-tumoral lesions were associated (p[lt]0,05) with a worse prognosis using both classifications. The rest of parameters were not associated with outcome in either classification.
CONCLUSIONS: Both outcome classifications, Engel[ssquote]s and ILAE[ssquote]s , were equally useful for correlation purposes in our series. New studies with more number of patients are necessary for corroborating our findings.
[Supported by: Vicente Villanueva was supported by a fellowship from the Spanish Neurological Society]