Abstracts

Rationale: Neurocysticercosis(NCC) is frequently associated with seizure complication. Perilesional brain edema around calcified lesion has been documented in several reports of patients presenting with NCC. The purpose of this study was to determine the association between the perilesional edema around calcified cysticerci and seizure attacks in Korean patient with NCC. Methods: We retrospectively reviewed medical records and brain computed tomography (CT) or magnetic resonance imaging (MRI) of the patents admitted with NCC. We divided the patients into two groups comprising the patients with seizures, and those with other neurological complications (such as headache, dizziness or motor-sensory symptoms). NCC findings on neuroimages were divided into: active cysts, calcified lesions without viable or degenerating cysts, and calcified perilesional edema around calcified lesion. Results: Between May 2004 and April 2016, 59 patients with NCC who meet the established diagnostic criteria have been evaluated using CT or MRI. Twenty-four (40.6%) of 59 patients with NCC had edematous calcified lesions. In multiple logistic regression analyses, calcified lesion around perilesional edema was associated with the seizure attack (aOR 3.38, 95% CI 1.13 to 10.11, p=0.03; adjusted for age and gender). Conclusions: In present study, the perilesional edema with calcified cysticerci was frequently found in Korean patients with NCC and it was associated with attacks of seizures. We recommend prophylactic antiepileptic drugs in NCC patients who have perilesional edema around calcified lesion. Funding: None