Risk Factors for SUDEP in a Population of Patients with Ictal Asystole
Abstract number :
3.202
Submission category :
Clinical Epilepsy-All Ages
Year :
2006
Submission ID :
6865
Source :
www.aesnet.org
Presentation date :
12/1/2006 12:00:00 AM
Published date :
Nov 30, 2006, 06:00 AM
Authors :
1C. P.J.A. Monte, 2J. B.A.M. Arends, and 2I.Y. Tan
Ictal asystole has been hypothesized to be a mechanism for SUDEP. The aim of this study is to analyse the presence of risk factors for SUDEP in a population of patients with a history of ictal asystole., Risk factors for SUDEP were determined in a submitted systematic review: young age, male sex, early onset, generalized tonic-clonic seizures and the presence of brain lesion. We than performed a literature search (pubmed, embase, cochrane library and references) for cases of ictal asystole and checked them for the presence of these risk factors., We identified 41 cases of ictal asytole. Male sex: n=39, 71%. Young age n=33, 66%. Generalized seizures n=10, 70%. Early onset n=20, 80%. Structural brainlesion n=31, 54%., The occurrence of the risk factors is similar in both populations. The statistical significance wil be discussed using a population of epilepsy patients, a population of patients known with ictal bradycardia and a population of patients with a history of asystole.,
Clinical Epilepsy