Screening Evaluation for Infantile Epileptic Spasm Syndrome by Single Sleep-wake Cycle on EEG
Abstract number :
1.195
Submission category :
4. Clinical Epilepsy / 4B. Clinical Diagnosis
Year :
2023
Submission ID :
47
Source :
www.aesnet.org
Presentation date :
12/2/2023 12:00:00 AM
Published date :
Authors :
Presenting Author: John Mason, MD – University of New Mexico
Elizabeth Juarez-Colunga, PhD – University of Colorado; Kelly Knupp, MD – Children's Hospital Colorado
Rationale: Infantile epileptic spasms syndrome (IESS) is a common and urgent diagnosis with seizure and nonseizure mimics. Evaluation with prolonged video EEG can be time-consuming and costly. This study investigated the use of electroencephalography (EEG) with review of a single sleep-wake cycle to exclude IESS and decrease electroencephalographic monitoring time.
Methods: We retrospectively reviewed video EEGs done at a single center for spell capture on children between the ages of two months and two years for the 18 months from January 2019 through June 2020. EEGs were reviewed from their beginning through the first sleep-wake cycle and scored as normal, consistent with IESS, or abnormal but not consistent with IESS. Scores were compared to the clinical report created by analysis of the entire video EEG.
Results: Two hundred thirty eight EEG studies met inclusion criteria. The mean age of patients at the time of study was 7.6 months. The median durations of full and first sleep-wake cycle recordings were 908 and 107.5 minutes respectively, with mean difference in recording time of 796 minutes, p-value < .01. Scoring outcomes were similar: 68% were scored as normal on first sleep-wake cycle review as compared to 63% (
Clinical Epilepsy