Abstracts

Rationale: To understand the clinical characteristics of pediatric stroke and compare it with the neonatal strokeMethods: Clinical and neuroimaging (MRI) findings were analysed retrospectively in 22 patients (12males, 10 females) aged from 1 days to 14 years at the time of diagnosis as stroke from August 2007 to March 2011.We defined neonatal stroke as the brain injury detected before 1 month of age, excluding germinal matrix hemorrhage or intraventricular hemorrhage only. We also excluded all kinds of stroke with traumatic origins.Results: Among 22 patients, eleven (8 males, 3 females) had the stroke within 1 month of age (median 4days, range 1 to 7days), 8 out of eleven were ischemic stroke with the symptom-onset at average 4days of age compared to 1 day in 2 hemorrhagic strokes. One had the sinovenous thrombosis. Multifocal infarction (n=4) and MCA infarction(n=3) were frequent sites involved. Seizure (n=6) was the most frequent presenting symptom. In the other eleven patients (4 males, 7 females), stroke was detected after the neonate (median 3.5years, range 2months to 14years) with various risk factors such as meningitis (n=2), perinatal insult (n=2), Moyamoya disease (n=2), MELAS (n=1), suspicious Hashimoto encephalopathy (n=1), Sturge-Weber syndrome (n=1). acute systemic condition (n=1), and cavernous hemangioma (n=1). Seizure (n=6) was the most frequent presenting symptoms.Conclusions: Seizure was the most frequent presenting symptom in neonatal and pediatric strokes. More broad work up to detect the pathophysiology about the pediatric stroke would be useful for early proper treatment and better prognosis.