Authors :
Presenting Author: Vasundhra Mahendra, MD – Medical University of South Carolina
Marina Buciuc, MD – Resident, Department of Neurology, Medical University Of South Carolina; Ekrem Kutluay, MD – Professor, Department of Neurology, Medical University Of South Carolina
Rationale:
Seizures are a well-established complication in neurosarcoidosis and have shown to be associated with an increased risk of morbidity and mortality. Comprehensive data on the possible risk factors associated with increased risk of seizures in patients with neurosarcoidosis remain limited. Identifying these factors may lead to early detection of patients at risk of having seizures and improvement in management and outcomes for patient with epilepsy in neurosarcoidosis.
Methods:
This is a retrospective case-control study of 38 patients with neurosarcoidosis investigating demographic, clinical, laboratory, MRI and Electroencephalography (EEG) characteristics associated with seizure development. Medical records of 600 patients aged between 18-65 years with a diagnosis of neurosarcoidosis who were seen from January 1st, 2011 and July 31st, 2022, at Medical University of South Carolina (MUSC), Charleston, were reviewed. Two-tailed Wilcoxon test or Fisher’s exact test were used for continuous or categorical variables, respectively, significant level set on p< 0.05.