SELECTIVE REORGANIZATION OF LANGUAGE SUB-TASKS IN A CHILD WITH A LEFT PARIETAL TUMOR
Abstract number :
2.183
Submission category :
Year :
2004
Submission ID :
4705
Source :
www.aesnet.org
Presentation date :
12/2/2004 12:00:00 AM
Published date :
Dec 1, 2004, 06:00 AM
Authors :
1Jeffrey Ojemann, 2Molly Warner, 3David Corina, 2Hillary Shurtleff, 2Heidi Blume, 4Ken Maravilla, 2Patti Murphy, 2Marcio Sotero, and 2John Kuratani
Language mechanisms are multiple, and subserved by different brain regions. In this case of a 15 year-old bilingual girl, functional MRI (fMRI) revealed a pattern of language representation that differed from the results of stimulation mapping and Wada testing As part of clinical evaluation, Wada testing, stimulation mapping of language during surgery using an object naming task, and langugae fMRI was performed. The language fMRI used both a semantic (meaning related) task and a phonologic (rhyme related) task. Both stimulation and fMRI studies used both English and Spanish. Wada testing in Spanish revealed a strong left lateralization for language. Stimulation mapping disrupted object naming just anterior to the tumor in both langauges. Functional MRI in both languages revealed left sided activation for the semantic task, but right sided activation for the phonologic task, in the homologous region from the tumor. She tolerated surgery well with no language deficits, even transient. Language lateralization can be dependent on task. Semantic tasks appear to drive the results of both Wada testing and stimulation mapping. (Supported by NS41272 (JGO))