Abstracts

Rationale: Self-Limited Childhood Epilepsy with Centrotemporal Spikes (CECTS), an epilepsy syndrome of unknown etiology, is the most common focal epilepsy of childhood. Patients with CECTS have impairments in different areas of Executive Functions (EF). Social cognition, one EF, represents a complex set of abilities that contribute to construct mental representations of social relations and to use them in the social interaction. Social cognition has been studied in different forms of epilepsy but remains neglected in CECTS (Genizi et al., 2012), as well as its relationship with classic EF, estimated IQ (IQe), age and epilepsy-related factors. In this context, this study aimed to: (i) evaluate social cognition in children with CECTS and its relation with classic EF, (ii) verify the relationship between neurodevelopmental aspects, IQe and age at epilepsy onset and the performance on social cognition, and (iii) identify the impact of epilepsy-related factors on social cognition task. Methods: We prospectively evaluated 23 patients with CECTS and 20 healthy controls. There was no difference in the gender, age, schooling, school type and IQe (Table 1). All participants underwent a comprehensive neuropsychological assessment and the Faux Pas Child Task (FP), which evaluates the recognition and comprehension of other people’s mental state. To evaluate differences on demographic aspects, IQe and performance in FP among the groups, t test and chi-square test were carried out as appropriate. We used Mann-Whitney test to analyze the relationship between neurodevelopmental aspects (