Surgery outcome in patients with drug-resistant epilepsy and calcified neurocysticercosis: experience at the National Institute of Neurology and Neurosurgery
Abstract number :
1.392
Submission category :
Camelice Poster
Year :
2021
Submission ID :
1886418
Source :
www.aesnet.org
Presentation date :
12/4/2021 12:00:00 PM
Published date :
Nov 22, 2021, 06:56 AM
Authors :
Jose Chang-Segura, MD - National Institute of Neurology and Neurosurgery; Karen Guzmán-Sánchez, Neurologist - National Institute of Neurology and Neurosurgery; Juan Cotuá-Urzola, Neurologist, Epilepsy Fellowship - National Institute of Neurology and Neurosurgery; Jimena Armenta-Báez, MD - National Institute of Neurology and Neurosurgery; Andrea Santos-Peyret, MD - National Institute of Neurology and Neurosurgery; Mario Sebastián-Diaz, MD - North Anáhuac University; Mario Alonso-Vanegas, Epilepsy Neurosurgeon - HMG Hospital Coayacan; Agnès Fleury, Neurologist - National Institute of Neurology and Neurosurgery; Iris Martínez-Juárez, Neurologist; Epileptologist - National Institute of Neurology and Neurosurgery
Rationale: Calcified neurocysticercosis (CNC) is a common cause of epilepsy, and everyday more cases of drug-resistant epilepsy (DRE) are seen in patients with CNC. (1,2). The prevalence of DRE in the NINNMVS was described as up to 56%, including 2.4% of patients with CNC who persisted with seizures. (3)
Objective: To describe the clinical characteristics and epilepsy surgery outcome in patients with DRE and calcified CNC.
Methods: A retrospective cross-sectional descriptive study was carried out with a total of 8 patients with DRE and CNC who received treatment with epilepsy surgery were evaluated. The SPSS program was used for statistical analysis.
Results: Half of the patients were women, and the mean onset age of epilepsy was 21 years (range 2 to 48 years). The clinical onset of the seizures was in the temporal lobe in 7/8 patients. 6/8 patients had a single CNC and 2/8 two. The most frequent localization of the CNC was the temporal lobe in 5/8 of the cases. Two right temporal lobectomies, two left temporal lobectomies, one left frontal lesionectomy, one left and one right amygdalohippocampectomy were performed. In a mean follow-up period of 7.4 years (range 4 to 10 years), 8/8 of the patients had a postsurgical Engel classification of IA.
Conclusions: In these series of cases presented after undergoing a pre-surgical evaluation all the patients were seizure-free in the postoperative period. The evaluation of epilepsy surgery is recommended in patients with FD with calcified NCC.
Funding: Please list any funding that was received in support of this abstract.: This abstract was support by the Mexican Chapter of the International League Against Epilepsy (CAMELICE) to be presented in the AES 2021 annual meeting.
Camelice Poster