Abstracts

To compare seizure outcome in the patients with cavernous angioma treated by lesionectomy alone or further resection and to analyze the factors influencing on the surgical outcome., Fifty-nine patients (27 male) with supratentorial cavernous angioma associate with seizure were operated in our institute. Clinical, radiological and electrophysiologic data were collected retrospectively. The mean age was 32 years (ranged 2-67) and the mean follow up duration after surgery was 34.3 months (ranged 12-103)., Thirty-two patients underwent lesionectomy and remaining 27 patients underwent standard temporal lobectomy with tumor removal. Seizure outcome was compared using the Engel classification scheme between two kinds of technique. At the last follow up, 33 patients were involved in Engel class I, 6 patients in class II, 4 patients in class III and 2 patients were class IV. Estimated survival in patients who had shorter seizure histories and fewer preoperative seizures did not differ between the two surgical techniques. The important factors influencing the outcome were duration of seizure, location of tumor, multiple epileptic foci on electroencephalogram and surgical technique., These findings indicated that shorter seizure histories and fewer preoperative seizures can be effectively treated by lesionectomy alone, whereas those with longer histories and more seizures are not effectively treated by this procedure and may require epileptic surgery. And early surgical intervention is important for good treatment outcome.,