Abstracts

Rationale:
Some studies have suggested that tumor pathology significantly influences freedom from seizures post epilepsy surgery; however, there is no consensus among researchers regarding this issue.   This study aimed to retrospectively investigate different types of tumor-related epilepsy and their outcomes in the first-year post epilepsy surgery.
Method:
In this hospital-based retrospective study, patients with drug-resistant epilepsy due to a brain tumor who underwent epilepsy surgery were included. The patients underwent a thorough presurgical evaluation in an Epilepsy Monitoring Unit (EMU) before deciding to undergo surgical intervention, according to an epilepsy case management conference. Four outcomes of interest were investigated during the first-year post epilepsy surgery.
Results:
One hundred patients with brain tumors were included in this study (male: female = 3:2); 45 patients were children. Most of the patients (93) had low-grade gliomas or glioneuronal tumors (G/GNT). No significant differences in outcome were observed between sex, age, or histopathological categories. However, during the first year after epilepsy surgery, most of the low-grade G/GNT cases showed favorable outcomes of International League Against Epilepsy (ILAE) class 1 and 2 (61.3% and 9.7%, respectively), while high-grade gliomas and meningothelial tumors showed outcomes of ILAE class 1 (40% and 100%, respectively).  
Conclusion:
Favorable outcomes were achieved in the first-year post epilepsy surgery for different brain tumors among both children and adults. Adequate presurgical evaluation in EMU (for long-term videoelectroencephalography monitoring) to plan an appropriate surgical strategy is recommended. Tumor Pathology does not influence seizure outcomes for one-year post epilepsy surgery.
Funding:
:Not applicable