Authors :
Presenting Author: Jaime-Dawn Twanow, MD – Nationwide Children's Hospital and The Ohio State University College of Medicine
Rae Leonor Guymayan, MD – Nationwide Children's Hospital and The Ohio State University College of Medicine; Darrah Haffner, MD – Nationwide Children's Hospital and The Ohio State University College of Medicine; Margie Ream, MD, PhD – Nationwide Children's Hospital and The Ohio State University College of Medicine; Laurel Slaughter, MD – Nationwide Children's Hospital and The Ohio State University College of Medicine; Jason Kovalcik, MD – Nationwide Children's Hospital and The Ohio State University College of Medicine; Trina Anthony, NNP – Nationwide Children's Hospital; Megan Rose, MPH, MS – Nationwide Children's Hospital Center for Clinical Excellence; Adam Ostendorf, MD – Nationwide Children's Hospital and The Ohio State University College of Medicine
Rationale:
Acute provoked seizures occur with an incidence of one to three per 1,000 infants during the first week of life.1 There is growing recognition of the need to balance the benefits of seizure management with the risks related to anti-seizure medications (ASM). 2 Recent recommendations provide management guidelines and a framework for weaning ASM in the acute provoked seizure population once the risk of seizures is decreased. 3,4
Using Quality Improvement (QI) methodology, we aimed to decrease the percentage of neonates in the Nationwide Children’s Hospital (NCH) Neonatal Intensive Care Unit (NICU) with acute provoked seizures discharged receiving an ASM from a baseline of 88% to <