His major research interest is inherited metabolic epilepsies with a specific focus on disorders of GABA metabolism. Dr. Pearl has published over 250 peer-reviewed manuscripts, over 160 chapters/reviews, and written or edited five books, one of which is translated into Chinese and one into Japanese. Dr. Pearl is a member of the Music and Health Institute at the Berklee College of Music in Boston, and is past president of the Professors of Child Neurology and the Child Neurology Society.