WD Gaillard is an internationally recognized for his work in pediatric epilepsy and imaging, work that has transformed clinical care and investigated the effect of epilepsy on brain structure and function. Working at CNH allowd a long and productive collaboration with Dr. William Theodore and the Intramural Clinical Epilepsy Section and extramural NINDS, initially with a K08 training award, and then as a guest researcher and Child Neurology/Epiepsy Consultant. These investigations examined the effect of epilepsy on brain structure, metabolism, and blood flow in children and adults. He conducted the first cognitive studies in children with fMRI. His corpus of work established to utility and effectiveness of mapping language networks in planning epilepsy surgery, including outcomes, and correlation with the Wada test, and invasive mapping. He established the utility MRI (in contrast to CT) for the evaluation of children with new onset seizures and epilepsy that are part of standard care. Later work has used fMRI to examine the nature and limitations to early brain placticity for cognitive systems. Current work employs rsfMRI to examine the local and network properties of focal epilepsy and seizure focus identification.
At CNH he directs an accomplished multidisciplinary team of pediatric epilepsy specialists and translational scientists to care for children and young adults with epilepsy from the onset of seizures, through novel therapeutic interventions, medication trials, and, when appropriate, surgery. His work has been continuously funded by the NIH, NSF, CDC, and several philanthropic foundations. His group plays a leading role in national and international collaborative efforts, databases, and registries in addition to industry and federal clinical trials, epidemiological studies, and device development.
In addition to serving as treasurer and president of the American Epilepsy Society he has served as Chair fo the ILAE Diganostics Commision, and member of the Pedatric Commision and the North American Epilepsy Commission in addition to several committees and task forces. He has published over 300 peer reviewed pulications and over 80 chapters/invited publications. He has trained many fellows, post docs, and junior faculty who lead successful academic and clinical careers. Awards include the AES Clinical Research Recognition Award, the Child Neurology Martha Bridge Denckla Award, and the ILAE Ambassador Award.