An Acute Histologic Analysis in Epileptic Patients with Bipolar Coagulation on Functional Cortexes.
Abstract number :
3.207
Submission category :
Year :
2001
Submission ID :
1953
Source :
www.aesnet.org
Presentation date :
12/1/2001 12:00:00 AM
Published date :
Dec 1, 2001, 06:00 AM
Authors :
W. Zhang, M.D., Neurobiology, Beijing Neurosurgical Institute, Beijing, China; G. Luan, M.D., Ph.D., Neurosurgery, Tiantan Hospital, Beijing, China; L. Yan, M.D., Neurobiology, Beijing Neurosurgical Institute, Beijing, China; C. Wang, M.D., Nerosurgery, B
RATIONALE: Bipolar Coagulation on Functional Cortexes () for treatment of the intractable epilepsy is a pilot surgical technique. The principle of is similar to Multiple subpial Transection (). We studied the pathalogical injury in different brain lobe after .
METHODS: An acute neuropathological analysis in 14 patients with epilepsy was performed, including frontal lobe 3 cases, occipital lobe 3 cases and tempple lobe 8 cases. was done befor lobectomy. The surfacees of mulitiple cerebral cortexes were coagulated in the bipolar output power 4 unit, at intervals 5 mm, and duration 1-2 seconds. the Hematoxylin-eosin(HE) was used to assess general pathological features.
RESULTS: There was coagulation necrosis in superficial layers (I-II)and acute pyknosis and tissue edema adjacent to the superficial layers(II-III). The structure of deep cortexes was almost normal in all cases..
CONCLUSIONS: These results indicated that low power of could produce fiber damage in superficial layers and thus would prevent horizontal synchronization and spread of epileptic discharges. The deep cerebral structure was normal after . It could be safe in useing clinic trial.