Abstracts

Rationale: Status Epilepticus (SE) is a neurological emergency with high mortality that often requires admission in Intensive Care Units (ICU). Several factors of worse outcome have been identified in prior studies. A recent study showed a surprisingly higher mortality in the ward than in the ICU but few data are available to explain this mortality after the ICU stay. The aim of our study was to determine the mortality in ICU and in the ward in patients with SE admitted to an ICU and to identify risk factors of mortality.

Methods: Retrospective case series of patients admitted to the ICU for treatment of SE or with SE identified during the ICU stay between January 1, 2015 and December 31, 2019. The primary outcome measure was mortality at ICU or hospital discharge.

Results: Mortality was associated with older age, lower GCS, higher STESS and EMSE scores, NCSE, need for mechanic ventilation and vasopressors, and burden of complications during their ICU stay, but not with refractoriness, or the use of continuous intravenous anesthetic drugs (CIVADs; see Table). No significant difference in clinical features was found between ICU and ward deaths, although ward deaths tended to less frequently have complications during ICU stay than ICU deaths but more frequently compared to survivors.

Conclusions: Both ward and ICU mortality in patients with SE admitted to an ICU are linked with a more severely etiology and a greater burden of complications during ICU stay rather than the refractoriness of SE itself.

Funding: Please list any funding that was received in support of this abstract.: Fonds Erasme.